Compounded NAD+ injections.

Injection-site reactions

The most common side effects of NAD+ injections happen where the needle goes in. You may notice redness, tenderness, mild swelling, bruising, or itching at the injection site. These reactions are usually mild and fade on their own within a day or two. Rotating your injection site with each dose can help.

Contact your care team if a reaction lasts more than a few days, spreads, feels increasingly warm or painful, or shows any drainage. Those can be early signs of infection and deserve prompt attention.

Flushing and nausea

NAD+ that enters the body quickly is associated with a distinct cluster of symptoms: facial flushing, a feeling of warmth or pressure in the chest, nausea, headache, and lightheadedness. These effects are most often linked to rapid administration and tend to ease when the medication is given more slowly.

Follow your prescribed dose and injection instructions exactly, and never increase your dose or pace on your own. If these symptoms occur and do not settle promptly, stop and message your care team before taking your next dose.

Limited long-term safety data

NAD+ therapy has not been studied as extensively as many established prescription medications, and long-term safety data in humans is still limited. That does not mean the therapy is unsafe. It means your provider is making a judgment based on the evidence available today, your health history, and ongoing monitoring.

This is one reason care through the edit includes regular check-ins and secure messaging with your care team rather than a one-time prescription. Report anything unexpected, even if it seems minor, so your provider can adjust your plan.

Who should avoid NAD+ injections

Compounded NAD+ is not recommended during pregnancy or while breastfeeding, because there is not enough safety data in these groups. If you become pregnant or begin trying to conceive during treatment, pause your injections and tell your provider.

If you have an active cancer diagnosis and are currently in treatment, do not start NAD+ without input from your oncologist. NAD+ plays a role in cellular energy metabolism, and your oncology team should weigh in before anything new is added to your regimen.

Always share your full health history during your consultation, including any history of cancer, liver or kidney disease, or heart conditions, so your provider can decide whether this therapy is right for you.

Medication and supplement interactions

Formal interaction studies for compounded NAD+ are limited, so your provider relies on a complete picture of everything you take. List every prescription medication, over-the-counter product, and supplement during your consultation, and update your care team whenever anything changes.

Do not add a new medication or supplement mid-course without checking in first. A quick message through the portal is all it takes.

Compounded medication disclosure

Compounded medications are prepared for an individual patient based on a prescription from a licensed provider.

Your NAD+ is compounded by The Pharmacy Hub, a licensed U.S. pharmacy, and shipped in temperature-controlled packaging to protect the medication in transit. A licensed provider at our affiliated medical practice, Arora Health & Aesthetics, LLC, prescribes it only after determining it is appropriate for you.

When to seek immediate care

Serious reactions to NAD+ injections are rare, but they require fast action. Call 911 or go to the nearest emergency room if you experience hives or a spreading rash, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing, chest pain, severe dizziness, or fainting.

Also seek same-day medical care for signs of a spreading injection-site infection, such as expanding redness, significant warmth, or fever. Once you are safe, let your care team know what happened so your treatment plan can be reviewed.

Questions

If anything on this page is unclear, or something about your treatment does not feel right, we want to hear from you. Email hello@theedithealth.com or send a secure message through the member portal at my.theedithealth.com. No question is too small.

This page is for education. Your provider's guidance always comes first.