Compounded tirzepatide.

Warning: possible thyroid tumors, including cancer

In rodent studies, tirzepatide caused thyroid C-cell tumors. It is not known whether tirzepatide causes thyroid C-cell tumors, including a type of thyroid cancer called medullary thyroid carcinoma (MTC), in people.

Do not use tirzepatide if you or any family member has ever had MTC, or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Tell your provider right away if you notice a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These can be symptoms of a thyroid tumor.

Who should not use tirzepatide

Do not use compounded tirzepatide if you have a personal or family history of MTC, if you have MEN 2, or if you have had a serious allergic reaction to tirzepatide or any of its ingredients. It may also not be appropriate if you have a history of severe gastrointestinal disease, including gastroparesis.

Share your complete health history and medication list during your consultation. Your provider uses that information to decide whether this medication is a safe option for you.

Pancreatitis

Inflammation of the pancreas, including severe and life-threatening cases, has been reported with medicines in this class. Stop using tirzepatide and get medical help right away if you develop severe pain in your stomach area that does not go away, with or without vomiting. The pain may spread from your abdomen to your back.

Gallbladder problems

Gallbladder problems, including gallstones, have occurred in people using tirzepatide, and some cases have required surgery. Contact your provider if you notice pain in your upper stomach, fever, yellowing of your skin or the whites of your eyes, or clay-colored stools.

Low blood sugar with insulin or sulfonylureas

Using tirzepatide together with insulin, or with medicines that increase insulin release such as sulfonylureas, raises the risk of low blood sugar. Your provider may need to adjust the dose of those medicines.

Symptoms of low blood sugar can include shakiness, sweating, dizziness, a fast heartbeat, intense hunger, blurred vision, confusion, or irritability. Tell your provider about every diabetes medicine you take before starting, and report any low blood sugar episodes promptly.

Kidney problems

Nausea, vomiting, or diarrhea can lead to dehydration, and dehydration can cause new kidney problems or make existing kidney disease worse. This has been reported with medicines in this class, including in people who had no prior kidney disease.

Stay hydrated, especially when starting or increasing your dose. Tell your provider if you have kidney disease, or if you cannot keep fluids down.

Serious allergic reactions

Serious allergic reactions, including anaphylaxis and swelling of the face, lips, tongue, or throat, have been reported with tirzepatide. Stop using the medication and seek emergency care immediately if you develop trouble breathing, severe rash or hives, rapid swelling, severe dizziness, or a racing heartbeat. Do not restart the medication unless your provider tells you it is safe to do so.

Pregnancy and breastfeeding

Do not use tirzepatide if you are pregnant, planning to become pregnant, or breastfeeding. It may harm a developing baby, and it is not known whether it passes into breast milk.

Tirzepatide may also make birth control pills less effective. Talk with your provider about using a backup, non-oral method of birth control for a period of time after starting and after each dose increase. If you become pregnant while using tirzepatide, stop the medication and contact your provider right away.

Common side effects

The most common side effects are digestive and include nausea, vomiting, diarrhea, constipation, decreased appetite, and stomach discomfort. They are usually most noticeable when you first start or when your dose increases, and they often ease as your body adjusts.

If side effects persist, interfere with daily life, or keep you from staying hydrated, message your care team through the member portal. Do not adjust your dose on your own.

Drug interactions

Tirzepatide slows stomach emptying, which can change how some oral medicines are absorbed. Use particular caution with insulin, sulfonylureas, and other medicines that lower blood sugar, and do not combine tirzepatide with any other GLP-1 or GIP medication.

Tell your provider about every prescription, over-the-counter medicine, and supplement you take so they can review your full regimen before prescribing.

Compounded medication disclosure

Compounded tirzepatide is prepared for you by The Pharmacy Hub, a licensed U.S. pharmacy, based on a prescription written by a licensed provider at Arora Health & Aesthetics, LLC after your consultation.

Tirzepatide is the active ingredient in the FDA-approved medications Mounjaro and Zepbound. Compounded tirzepatide is not affiliated with, endorsed by, or a substitute for those products, and no claim of equivalence is made. Your medication ships directly to you in temperature-controlled packaging.

When to seek immediate care

Call 911 or go to the nearest emergency room if you experience severe stomach pain that will not go away, trouble breathing, swelling of your face, lips, tongue, or throat, symptoms of severe low blood sugar such as confusion or loss of consciousness, or signs of severe dehydration such as being unable to keep fluids down.

Contact your provider promptly, without waiting for your next check-in, if you notice a neck lump or swelling, hoarseness, trouble swallowing, yellowing of your skin or eyes, upper stomach pain with fever, or a significant change in urination.

Questions

Your care team is here for this. Message us any time through the member portal at my.theedithealth.com, where secure messaging connects you directly with your care team, or email hello@theedithealth.com. If anything on this page is unclear, ask before you take your first dose.