Biest 50:50
CompoundedWomen's healthBi-estrogen
Starting at $139 / month
Biest 50:50 is a compounded blend of two estrogens, estradiol and estriol, in a 50:50 ratio, applied as a topical cream. Available on its own or combined with progesterone. Prescribed and dosed by a licensed provider.
Prescription format
Topical cream
A measured amount of cream applied to the skin as directed by your provider.
Full refund if you are not approved. Prescriptions are issued only if a licensed provider determines treatment is appropriate for you.
- Prescription medication
- Topical cream
- Optional progesterone pairing
- Temperature-controlled 2-day shipping
What it supports
Care for the menopause transition.
Biest combines two estrogens in one topical cream, compounded to your prescription. Your provider sets the strength and can add progesterone when appropriate.
Hot flashesNight sweatsSleepMoodEnergy
Benefits
What it gives back.
Two estrogens, one cream
Estradiol and estriol together, applied topically.
Made for you
Compounded to the strength your provider sets.
Simple to use
A measured amount of cream, on your schedule.
Who it's for
Care for the menopause transition.
Symptoms are disruptive. Hot flashes, night sweats, sleep, mood, or energy are affecting your day.
You want the right form. A provider matching the hormone and delivery to your history and preferences.
Ongoing, not one-and-done. Your dose is reviewed and adjusted over time, not set and forgotten.
FAQ
Common questions.
Find out more about Biest 50:50.
Biest combines two estrogens in one topical cream, compounded to your prescription. Your provider sets the strength and can add progesterone when appropriate.
A measured amount of cream applied to the skin as directed by your provider.
Biest is available on its own or as Biest 50:50 with progesterone. Your provider recommends the option that fits your history.
Estrogen-containing therapy is not appropriate for everyone. Your provider screens your history before prescribing.
Availability varies by state and is confirmed during your intake.
Compounded hormone medications are prepared by a licensed U.S. compounding pharmacy and are not FDA-approved. They may be prescribed off-label at a licensed provider's discretion when appropriate. Availability varies by state. This is educational information, not medical advice.
Related treatments
Explore more.
Start today
Biest 50:50.
A licensed provider reviews your intake and prescribes Biest 50:50 if it is appropriate for you, with refills shipped to your door and your dose adjusted over time.
Start your visitImportant safety information. Compounded hormone medications are prepared by a licensed U.S. compounding pharmacy and are not FDA-approved. They are prescribed only when a licensed provider determines treatment is appropriate after reviewing your health history. This page is for informational purposes and is not medical advice. Individual results vary. Hormone therapy carries risks; discuss your personal history with your provider.
